Differential processing of proenkephalin-A by human peripheral blood monocytes and T lymphocytes.
نویسندگان
چکیده
منابع مشابه
Differential processing of proenkephalin-A by human peripheral blood monocytes and T lymphocytes.
Human peripheral blood mononuclear cells are analyzed for preproenkephalin gene expression and peptide processing. Met-enkephalin immunoreactivity as detected with a specific antiserum is found in the cytoplasm of monocytes but not in T lymphocytes. Secretion of met-enkephalin was analyzed with an RIA that is specific for the met-enkephalin pentapeptide. Unfractionated PBMC spontaneously releas...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1991
ISSN: 0021-9738
DOI: 10.1172/jci115382